Evidence Hub
Track evidence momentum and emerging diabetes research intelligence. Monitor relationship strength changes, identify accelerating evidence, and explore validated research insights.
Early access โ Evidence base actively growing
Last updated: 7/1/2026
Featured Evidence Topics
Start here to explore the most useful evidence topics.
HbA1c Reduction
What helps lower HbA1c in diabetes?
Weight Loss
What helps with weight loss in diabetes?
Glycemic Control
What improves glycemic control in diabetes?
Insulin Resistance
What improves insulin resistance in diabetes?
Prediabetes
What helps with prediabetes?
Diabetic Kidney Disease
What helps diabetic kidney disease?
What's New in the Evidence
Recent research signals, evidence movement, and emerging areas worth watching.
Featured Evidence Shift
Insulin glargine/lixisenatide fixed-ratio combination (iGlarLixi) โ Total daily insulin dose
Strongest evidence in the database
This relationship has 2 studies with moderate evidence, representing the most robust finding in our evidence base.
Temporal Intelligence Coming Soon
Evidence trends, state changes, and momentum history will activate once monthly snapshots accumulate. Requires at least two monthly evidence snapshots. Temporal intelligence will activate once historical data accumulates.
Explore by Health Goal
Find evidence by the outcome people are trying to improve.
HbA1c Reduction
Evidence related to lowering or improving HbA1c/A1C in diabetes management.
Weight Loss
Evidence related to body weight reduction, BMI improvement, waist circumference, and body composition changes.
Glycemic Control
Evidence related to blood glucose control, fasting glucose, postprandial glucose, glucose variability, and time in range.
Cardiometabolic Risk
Evidence related to blood pressure, lipid profile, cardiovascular risk, cardiovascular events, and cardiometabolic risk markers in diabetes.
Treatment Adherence
Evidence related to treatment adherence, medication use, physical activity participation, step count, diet intake, fruit and vegetable intake, and...
Explore by Treatment Type
Find evidence by treatment category, care approach, or lifestyle strategy.
Diabetes Technology
Evidence related to continuous glucose monitoring, insulin pumps, hybrid closed-loop systems, telemonitoring, mobile apps, digital health programs,...
Diabetes Self-Management Education
Evidence related to DSMES, diabetes education, self-management programs, case management, remote education, knowledge, adherence, and self-care beh...
Dietary Patterns
Evidence related to dietary patterns and nutrition strategies for diabetes, including low-carbohydrate, Mediterranean, ketogenic, low-glycemic-inde...
Supplements and Nutraceuticals
Evidence related to vitamins, minerals, probiotics, synbiotics, botanicals, and nutraceutical supplements studied in diabetes.
Explore by Condition
Find evidence by diabetes-related conditions, risks, or complications.
Insulin Resistance
Evidence related to improving insulin resistance, insulin sensitivity, fasting insulin, C-peptide levels, and beta-cell function in diabetes and pr...
Prediabetes
Evidence related to preventing or delaying type 2 diabetes, reducing diabetes incidence, and improving metabolic risk in people with prediabetes.
Diabetic Kidney Disease
Evidence related to diabetic kidney disease, albuminuria, kidney function, nephropathy progression, end-stage renal disease, and kidney-protective...
Diabetic Neuropathy
Evidence related to diabetic neuropathy incidence, neuropathy progression, neuropathic pain, balance, mobility, and interventions studied for nerve...
Diabetic Retinopathy
Evidence related to diabetic retinopathy incidence, retinopathy progression, microvascular complications, and diabetes interventions studied for ey...
Hypoglycemia
Evidence related to hypoglycemia events, severe hypoglycemia, time below range, postprandial hypoglycemia, symptom recognition, and diabetes interv...
Gestational Diabetes
Evidence related to gestational diabetes prevention, treatment, pregnancy weight gain, insulin-treated gestational diabetes, and maternal or perina...
Specialized Evidence Topics
Focused measurement and research-area topics.
Inflammatory and Vascular Markers
Evidence related to inflammatory, oxidative stress, endothelial, and vascular biomarkers measured in diabetes studies.
Adverse Events and Safety
Evidence related to adverse events, serious safety outcomes, gastrointestinal events, urinary tract infections, DKA, hyperglycemia, and treatment t...
Evidence Snapshot
View grouped archiveStrongest Evidence Relationship
GLP-1 Receptor Agonists โ Lipid Profile
Research Documents Analyzed
Peer-reviewed studies in evidence base
Strong Evidence Areas
Relationships with strong or very strong ratings
Most Consistent Finding
GLP-1 Receptor Agonists โ Glycemic Control
Evidence Pairs Analyzed
Intervention-outcome combinations
Most Studied Relationship
Lifestyle Programs โ Body Weight
Most Validated Relationships
Intervention-outcome relationships with the strongest evidence validation and replication
| Relationship | Evidence Strength | Studies | Consistency | Actions |
|---|---|---|---|---|
GLP-1 Receptor Agonists โ Lipid Profile | Emerging | 1(Single study) | unclear | |
Thiazolidinediones โ Lipid Profile | Emerging | 1(Single study) | unclear | |
Mediterranean Diets โ Diabetes Incidence and Prevention | Emerging | 2 | consistent | |
Metformin Therapies โ Blood Pressure | Emerging | 1(Single study) | unclear | |
Metformin Therapies โ Lipid Profile | Emerging | 1(Single study) | unclear | |
Insulin Therapies โ Kidney Function | Emerging | 2 | unclear |
Scroll horizontally to see all columns
Evidence by intervention and outcome groups
User-facing rows summarize related intervention-outcome pairs. Expand in the archive for atomic evidence detail.
Evidence Collections
Curated collections of evidence organized by strength, topic, and clinical relevance
Most Consistent Findings
Relationships with highly consistent results across studies.
Results show strong agreement across different populations and study designs.
Signals reliability and reproducibility of findings.
Technology-Based Interventions
Evidence for digital health and monitoring technologies.
Includes CGM, mobile apps, telehealth, and digital therapeutics.
Shows emerging evidence for technology-enabled diabetes management.
Pharmaceutical Evidence
Evidence for medication and drug interventions.
Includes all pharmaceutical interventions from GLP-1s to insulin regimens.
Core pharmacological evidence base for diabetes treatment.
Lifestyle Interventions
Evidence for diet, exercise, and behavioral approaches.
Non-pharmacological approaches to diabetes management.
Foundation of first-line diabetes prevention and management strategies.
All Categories
All major intervention and outcome categories in one place
| Category | Type | Interventions / Outcomes | Evidence Pairs | Strongest Evidence | View |
|---|---|---|---|---|---|
| Medications | intervention | 102 | 195 | Moderate | View category โ |
| Physical Activity | intervention | 42 | 67 | Emerging | View category โ |
| Supplements | intervention | 61 | 118 | Emerging | View category โ |
| Behavioral & Lifestyle | intervention | 65 | 117 | Emerging | View category โ |
| Diet and Nutrition | intervention | 41 | 70 | Emerging | View category โ |
| Devices & Technology | intervention | 28 | 43 | Emerging | View category โ |
| Control | intervention | 1 | 2 | Limited | View category โ |
| Procedures | intervention | 4 | 7 | Emerging | View category โ |
| Glycemic Control | outcome | 87 | 193 | Moderate | View category โ |
| Safety | outcome | 35 | 48 | Emerging | View category โ |
| Metabolic Health | outcome | 52 | 180 | Emerging | View category โ |
| Weight & Anthropometrics | outcome | 35 | 68 | Moderate | View category โ |
| Adherence & Engagement | outcome | 14 | 19 | Emerging | View category โ |
| Patient Reported | outcome | 19 | 37 | Emerging | View category โ |
| Clinical Outcomes | outcome | 30 | 74 | Emerging | View category โ |