Outcome topic
Evidence related to lowering or improving HbA1c/A1C in diabetes management.
340 Studies
Diabetes evidence, synthesized.
Organizing diabetes research into clear, evidence-based insights powered by the Evidence Intelligence™ framework.
Ask practical questions about diabetes treatments, outcomes, nutrition, exercise, and more — and see the evidence behind every answer.
Explore Questions Start with published questions and the evidence behind each answer.Explore the Evidence Browse evidence topics, studies, and research relationships.
Evidence Intelligence
1,098
Published Research
5,837
Evidence Relationships
654
Interventions With Evidence
1,758
Outcomes With Evidence
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Questions answered by the evidence
Explore practical diabetes questions with concise answers and direct access to the evidence behind them.
Adverse Events and Safety
Does Semaglutide reduce adverse events incidence?
Semaglutide may reduce adverse events incidence.
Read the answerCardiometabolic Risk
Does Exercise therapy improve systolic blood pressure?
Exercise therapy appears to improve systolic blood pressure.
Read the answerDiabetes Self-Management Education
Does DSMES improve diabetes self-management behaviors?
DSMES may improve diabetes self-management behaviors.
Read the answerDiabetes Technology
Does Hybrid closed-loop system improve time in range?
Hybrid closed-loop system may improve time in range.
Read the answerDiabetic Kidney Disease
Does Dapagliflozin improve urinary albumin-to-creatinine ratio?
Dapagliflozin may improve urinary albumin-to-creatinine ratio.
Read the answerDiabetic Neuropathy
Does Exercise therapy improve quality of life?
Exercise therapy may improve quality of life.
Read the answer
Answer provenance
How deDiabetes answers a question
See how a question connects to evidence relationships, supporting research, and an evidence-based answer.
Question
Does Exercise therapy improve systolic blood pressure?
Evidence Connection
Intervention
Exercise therapy
Outcome
Cardiometabolic Risk
Strong
Consistent
Supporting research
3 published studies · 3 RCTs
Published studies that contribute to this relationship.
Evidence-based answer
Exercise therapy appears to improve systolic blood pressure.
See the full answerExplore diabetes evidence
Evidence Topics let you browse synthesized evidence by topic. Evidence Explorer lets you search interventions, outcomes, evidence relationships, and supporting research.
Outcome topic
Evidence related to body weight reduction, BMI improvement, waist circumference, and body composition changes.
197 Studies
Outcome topic
Evidence related to blood glucose control, fasting glucose, postprandial glucose, glucose variability, and time in range.
232 Studies
What does the evidence say?
Clinical Reference
Structured intervention-focused evidence for deeper clinical review.
Clinical Reference
Cardiovascular Risk
5
Evidence assertions
37
Included studies
Explore the evidence by intervention, assertion, and supporting research.
Explore Clinical ReferenceClinical Reference
Glycemic Control
23
Evidence assertions
112
Included studies
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Explore Clinical ReferenceClinical Reference
HbA1c Reduction
41
Evidence assertions
195
Included studies
Explore the evidence by intervention, assertion, and supporting research.
Explore Clinical ReferenceLiving Evidence
Always Up to Date
New studies continuously strengthen, refine, or challenge existing evidence. Follow what matters and see what's changed.
115
New studies this week
84
New relationships this week
89
Evidence changes this week