Evidence Question

Does Dapagliflozin improve Estimated glomerular filtration rate?

Related to: Diabetic Kidney Disease

Short answer

Dapagliflozin may improve Estimated glomerular filtration rate.

How the evidence connects

Each connection shows the published evidence classification for that intervention and outcome relationship.

Intervention

Dapagliflozin

Intervention

Moderate
Mixed

2 studies · 2 RCTs

Outcome

Estimated glomerular filtration rate

Outcome

Why do we say this?

Across 2 randomized trials, findings are mixed and showed an effect on estimated glomerular filtration rate with Dapagliflozin.

What to keep in mind

Some evidence reported benefits while other evidence found little or no effect.

  • Only a small number of supporting studies are available.

Explore the evidence