Last updated June 2, 2026
Key finding
In a 6-month randomized trial of 168 elderly patients with type 2 diabetes after off-pump CABG, structured multidisciplinary case management improved cardiac function, HbA1c, walking distance, lipids, and quality-of-life outcomes versus routine care.
This trial tested a structured case management program in older adults with type 2 diabetes recovering from off-pump CABG. Compared with routine care alone, the program improved heart function, HbA1c, walking distance, lipid measures, and patient-reported recovery over 6 months.
Quick read
The essential study design details in one scan.
EvidenceScore™
High
Study type
Randomized Controlled Trials (RCTs)
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
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Study focus
In a 6-month randomized trial of 168 elderly patients with type 2 diabetes after off-pump CABG, structured multidisciplinary case management improved cardiac function, HbA1c, walking distance, lipids, and quality-of-life outcomes versus routine care.
Published in
Publication details and source links for this paper.
Zhai W, Yu H, Li Y, Zhang L, Li Q. Improved cardiac function and glycemic control in elderly diabetic patients through structured case management after CABG. Med Sci Monit. 2026;32:e952109. doi:10.12659/MSM.952109
Structured case management ↑ left ventricular ejection fraction at 6 months
Structured case management ↓ HbA1c, triglycerides, total cholesterol, and LDL cholesterol
Structured case management ↑ walking distance, quality of life, and daily living scores
Evidence network
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This study contributes evidence to Structured multidisciplinary case management and 6-minute walk distance, Activities of daily living, HDL cholesterol, and 8 more.
This study contributes evidence to
Primary intervention
Structured multidisciplinary case management
Primary outcomes
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
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Evidence pairs
301
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Contributes evidence
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Contributes evidence
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Contributes evidence
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Primary evidence
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Core evidence
The primary outcomes reported in this study.
Structured multidisciplinary case management → 6-minute walk distance
Structured multidisciplinary case management → 6-minute walk distance
Structured multidisciplinary case management → Activities of daily living
Structured multidisciplinary case management → Activities of daily living
Structured multidisciplinary case management → HbA1c
Structured multidisciplinary case management → HbA1c
Structured multidisciplinary case management → HDL cholesterol
Structured multidisciplinary case management → HDL cholesterol
Structured multidisciplinary case management → LDL cholesterol
Structured multidisciplinary case management → LDL cholesterol
Structured multidisciplinary case management → Left ventricular ejection fraction (LVEF)
Structured multidisciplinary case management → Left ventricular ejection fraction (LVEF)
Structured multidisciplinary case management → Left ventricular end-diastolic diameter
Structured multidisciplinary case management → Left ventricular end-diastolic diameter
Structured multidisciplinary case management → Left ventricular end-systolic diameter
Structured multidisciplinary case management → Left ventricular end-systolic diameter
Structured multidisciplinary case management → Quality of life
Structured multidisciplinary case management → Quality of life
Structured multidisciplinary case management → Total cholesterol
Structured multidisciplinary case management → Total cholesterol
Structured multidisciplinary case management → Triglycerides
Structured multidisciplinary case management → Triglycerides
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Older adults aged 65 years or above
The intervention was multi-component, so the study cannot isolate which component mattered most
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Diabetes Self-Management Education and Support (DSMES) Programs and HbA1c, Diabetes Self-Management Education and Support (DSMES) Programs and Cardiovascular Outcomes.
This study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Behavioral & Lifestyle
Behavioral & Lifestyle
Curated evidence collections and hubs this study is part of.
All studies on Diabetes Self-Management Education and Support (DSMES) Programs
Contributes to Diabetes Self-Management Education and Support (DSMES) Programs evidence base.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies measuring Adipokine and Angiogenic Markers
Measures Adipokine and Angiogenic Markers as a key outcome.
All studies measuring Cardiovascular Outcomes
Measures Cardiovascular Outcomes as a key outcome.
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2 results
1 results
2 results
2 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Diabetes Self-Management Education and Support (DSMES) Programs appears to improve Quality of Life Outcomes.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Quality of life
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 10 supporting studies with consistent results and a positive effect signal.
Limitations
Diabetes Self-Management Education and Support (DSMES) Programs may improve HbA1c.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 30 supporting studies with generally consistent results and a positive effect signal.
Limitations
Diabetes Self-Management Education and Support (DSMES) Programs may improve Adipokine and Angiogenic Markers.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
HDL cholesterol
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
LDL cholesterol
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Total cholesterol
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 7 supporting studies with consistent results and a positive effect signal.
Limitations
Diabetes Self-Management Education and Support (DSMES) Programs appears to improve Activities of Daily Living.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Activities of daily living
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 4 supporting studies with consistent results and a positive effect signal.
Limitations
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