Weekly evidence changelog

What Changed This Week

Week of September 7-13, 2026Generated Sep 12, 2026

A weekly summary of studies, interventions, outcomes, and evidence relationships added to Dediabetes.

Changes reflect content added to Dediabetes during this week and may include studies published earlier.

Permanent link to this weekly snapshot
240
New Studies
98
New Evidence Relationships
0
New Interventions
0
New Outcomes
91
Evidence Upgrades
7
Evidence Downgrades

Featured

Notable Changes

The most notable evidence graph changes detected in this weekly snapshot.

Notable Change

Aerobic Exercise -> Blood Pressure

0 new supporting studies0 total supporting studies
Notable Change

Aerobic Exercise -> Body Composition

0 new supporting studies0 total supporting studies
Notable Change

Aerobic Exercise -> Body Weight

0 new supporting studies0 total supporting studies
Notable Change

Aerobic Exercise -> Adipokine and Angiogenic Markers

Aerobic ExerciseAdipokine and Angiogenic Markers

Aerobic Exercise · Adipokine and Angiogenic Markers

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies2 total supporting studies
Notable Change

Aerobic Exercise -> Beta-cell Function

Aerobic ExerciseBeta-cell Function

Aerobic Exercise · Beta-cell Function

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
Notable Change

Aerobic Exercise -> C-peptide Levels

Aerobic ExerciseC-peptide Levels

Aerobic Exercise · C-peptide Levels

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study

New relationships

New Evidence Relationships

Showing the top 10 relationships first from content added to Dediabetes during this week.

New Evidence Relationship

Aerobic Exercise -> Adipokine and Angiogenic Markers

Aerobic ExerciseAdipokine and Angiogenic Markers

Aerobic Exercise · Adipokine and Angiogenic Markers

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies2 total supporting studies
New Evidence Relationship

Aerobic Exercise -> Beta-cell Function

Aerobic ExerciseBeta-cell Function

Aerobic Exercise · Beta-cell Function

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> C-peptide Levels

Aerobic ExerciseC-peptide Levels

Aerobic Exercise · C-peptide Levels

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> Cardiovascular Outcomes

Aerobic ExerciseCardiovascular Outcomes

Aerobic Exercise · Cardiovascular Outcomes

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies2 total supporting studies
New Evidence Relationship

Aerobic Exercise -> Carotid Intima-Media Thickness

Aerobic ExerciseCarotid Intima-Media Thickness

Aerobic Exercise · Carotid Intima-Media Thickness

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> Diabetes Incidence and Prevention

Aerobic ExerciseDiabetes Incidence and Prevention

Aerobic Exercise · Diabetes Incidence and Prevention

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> Glucose Variability

Aerobic ExerciseGlucose Variability

Aerobic Exercise · Glucose Variability

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies2 total supporting studies
New Evidence Relationship

Aerobic Exercise -> Inflammatory Markers

Aerobic ExerciseInflammatory Markers

Aerobic Exercise · Inflammatory Markers

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> Left Ventricular Structure

Aerobic ExerciseLeft Ventricular Structure

Aerobic Exercise · Left Ventricular Structure

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> Muscular Strength

Aerobic ExerciseMuscular Strength

Aerobic Exercise · Muscular Strength

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study

Studies

New Studies Added

Studies added to the Dediabetes evidence system during this weekly snapshot.

RCTsAdded Sep 9, 2026

ACT Improves Psychological Outcomes for Adolescents with Type 1 Diabetes

This study evaluated the feasibility and acceptability of Acceptance and Commitment Therapy (ACT) for adolescents with Type 1 Diabetes. Results indicated improvements in quality of life and reductions in diabetes distress for the ACT group.

Acceptance and Commitment Therapy (ACT)Diabetes distress scoresMindfulness+1 more
RCTsAdded Sep 10, 2026

AHCL Improves Glycemic Control in Adults with Type 1 Diabetes

This study evaluated the effectiveness of an Advanced Hybrid Closed Loop (AHCL) system compared to Multiple Daily Injections (MDI) plus Real-Time Continuous Glucose Monitoring (RT-CGM) in adults with Type 1 diabetes, finding significant improvements in HbA1c and time in range for the AHCL group.

Continuous glucose monitoringHybrid closed-loop systemHbA1c+1 more
RCTsAdded Sep 9, 2026

Aloe Vera Improves Diabetic Foot Ulcer Healing

This study evaluated the effectiveness of topical aloe vera extract in improving the healing of diabetic foot ulcers compared to standard care.

Topical aloe vera extractHigh improvement in BWAT scoreWound healing rate measured by reduction in ulcer size+1 more
RCTsAdded Sep 10, 2026

Atorvastatin may slow beta cell decline in type 1 diabetes

This study investigated the effects of atorvastatin on beta cell function in type 1 diabetes, finding that atorvastatin may enhance stimulated C-peptide secretion in certain subgroups.

AtorvastatinC-peptideCorrelation of baseline CRP levels with C-peptide outcome
RCTsAdded Sep 9, 2026

Automated insulin delivery reduces hypoglycemia risk

This study evaluated the impact of automated insulin delivery on hypoglycemia risk in adults with Type 1 diabetes, finding significant reductions in time below range.

Hybrid closed-loop systemInsulin pumpMean sensor glucose+4 more
RCTsAdded Sep 9, 2026

Bluetooth glucometers may reduce emergency visits in diabetes care

This study evaluated the effectiveness of Bluetooth-enabled glucometers compared to traditional glucometers in telehealth insulin titration for diabetes management, finding significant reductions in HbA1c levels.

Bluetooth-enabled glucometers (BTG)Traditional blood glucose meter (BGM)Diabetes distress scores+2 more
RCTsAdded Sep 9, 2026

Breastfeeding Rates Unchanged by Counseling in Diabetic Women

This study examined breastfeeding rates among women with pre-gestational diabetes mellitus through a randomized controlled trial. It found that confidence in breastfeeding knowledge significantly improved after face-to-face instruction.

Face-to-face instruction with a certified lactation consultantWritten information for controlsWritten information on breastfeeding+8 more
RCTsAdded Sep 10, 2026

Ceylon cinnamon extract lowers fasting blood sugar in T2DM.

The study evaluated the effects of Cinnamomum zeylanicum extract on LDL-C and fasting blood sugar in participants with T2DM, finding no significant reduction in LDL-C but a notable decrease in fasting blood sugar.

Cinnamomum zeylanicumASTAlanine Aminotransferase (ALT)+9 more
RCTsAdded Sep 10, 2026

CGM Improves Glycemic Control in Hospitalized Diabetes Patients

This study evaluated continuous glucose monitoring (CGM) versus point-of-care testing (POC) in hospitalized patients with type 2 diabetes, finding that CGM significantly improved time in range.

Continuous glucose monitoringPoint-of-care glucose testing (POC)Change in prandial insulin requirement per kg+2 more
RCTsAdded Sep 9, 2026

CGM Improves Glycemic Management in Type 2 Diabetes

This study compared continuous glucose monitoring (CGM) to blood glucose monitoring (BGM) in adults with type 2 diabetes, finding significant improvements in HbA1c and time in range with CGM.

Continuous glucose monitoringHbA1cTime >250 mg/dL+2 more
RCTsAdded Sep 9, 2026

Chewing gum may improve blood sugar control in gestational diabetes

This study evaluated the effect of chewing gum on glycemic control in women with gestational diabetes mellitus. The gum-chewing group showed lower fasting and postprandial blood glucose levels compared to the control group.

Chewing Gum InterventionControl: Routine CareAPGAR Score at 1 Minute+9 more
RCTsAdded Sep 9, 2026

CMNT diet may maintain diabetes remission for three years

This study investigated the effects of a Chinese Medical Nutrition Therapy (CMNT) diet on type 2 diabetes remission, finding significant improvements in diabetes-related outcomes.

Chinese Medical Nutrition Therapy (CMNT) diet interventionAll-cause mortalityBody weight+6 more
RCTsAdded Sep 10, 2026

Combined Training and Astaxanthin Improve Diabetes Management

This study investigated the effects of astaxanthin supplementation and combined training on metabolic indices in women with type 2 diabetes, finding significant improvements in certain outcomes.

Astaxanthin supplementationResistance trainingChange in microRNA-126 expression+7 more
RCTsAdded Sep 9, 2026

Community health worker intervention improves adherence in diabetes patients

This study evaluated a community health worker-led health literacy intervention aimed at improving adherence to lifestyle changes and medication in diabetes and hypertension patients in Harare, Zimbabwe.

CHW-led health literacy interventionAdherence to Mediterranean diet measured using MEDAS-14Adherence to alcohol moderation+8 more
RCTsAdded Sep 9, 2026

Depressive symptoms linked to worse metabolic profile in postpartum women

This study examined the relationship between depressive symptoms and metabolic profiles in women with prior gestational diabetes mellitus, finding significant associations with anxiety and metabolic syndrome.

Lifestyle intervention for prediabetesAnxiety level (STAI-6 scores)Depressive symptoms prevalence+3 more
RCTsAdded Sep 9, 2026

Diabetes and PCI Linked to Higher 10-Year Mortality

This study examined long-term outcomes in patients with left main coronary artery disease and diabetes undergoing PCI, revealing significant mortality differences based on diabetes treatment.

Percutaneous coronary intervention (PCI)All-cause mortalityCardiac death+5 more
RCTsAdded Sep 10, 2026

Dietitian support improves weight loss in type 2 diabetes

The Diabetes Remission Clinical Trial (DiRECT) evaluated a dietitian-supported low-energy total diet replacement intervention for participants with diabetes, focusing on weight loss and dietary changes.

DiRECT interventionUsual careAcceptability of mHealth intervention+5 more
RCTsAdded Sep 12, 2026

Dulaglutide and Dapagliflozin Improve Arterial Stiffness in Diabetes

A twelve-month treatment with dulaglutide and dapagliflozin significantly improved arterial stiffness and reduced albuminuria in patients with type 2 diabetes.

Combination of dulaglutide and dapagliflozinDipeptidyl peptidase-4 inhibitorsFemoral-ankle pulse wave velocity (faPWV) during acute hyperglycemia+4 more
RCTsAdded Sep 9, 2026

Early AID improves outcomes for youth with Type 1 diabetes

This study evaluated the early initiation of Automated Insulin Delivery (AID) in youth with Type 1 Diabetes from underresourced backgrounds. It found that AID showed potential benefits in satisfaction but did not significantly improve time in range compared to usual care.

Hybrid closed-loop systemUsual careDiabetes Distress in Caregivers+4 more
RCTsAdded Sep 9, 2026

Early meal timing improves nocturnal glucose levels.

This study investigated the impact of early meal timing on glucose levels in pregnant individuals with gestational diabetes, finding lower nocturnal glucose levels in the early eating group.

Continuous glucose monitoring2-hour plasma glucoseChange in diurnal mean glucose levels+4 more
RCTsAdded Sep 9, 2026

EB-CPG-based care improves T2DM management in Nepal

This study explored the experiences of Ayurvedic practitioners and patients with EB-CPG-based care for managing T2DM in Nepal, revealing predominantly positive experiences.

Integrated multidisciplinary diabetes and kidney care programUsual clinical practiceChallenges in usual clinical care+3 more
RCTsAdded Sep 9, 2026

Empagliflozin improves symptoms in diabetic neuropathy

The study investigated the effects of empagliflozin on glycaemic control and neuropathic symptoms in patients with type 2 diabetes and peripheral neuropathy, showing significant improvements in several key outcomes.

EmpagliflozinAmplitudeChange in Michigan Neuropathy Screening Instrument score+6 more
RCTsAdded Sep 12, 2026

Exercise improves adropin levels and reduces arterial stiffness in women with T2D

This study examined the impact of 12 weeks of combined aerobic-resistance training on adropin levels and arterial stiffness in women with type 2 diabetes (T2D). The exercise group showed significant improvements in adropin levels and reduced arterial stiffness.

Moderate continuous exerciseSupervised Multicomponent Exercise (MCE)Cardio-ankle vascular index (CAVI)+1 more
RCTsAdded Sep 12, 2026

Exercise Improves Gene Expression in Type 2 Diabetes

This study investigated the effects of different exercise types on gene expression in individuals with Type 2 Diabetes, finding increased CHRFAM7A expression post-exercise.

Aerobic exerciseMixed exerciseTaichi plus resistance band training+2 more
RCTsAdded Sep 12, 2026

Exercise improves insulin resistance and diabetes risk

This study evaluated the effects of multiple exercise interventions on lipoprotein insulin resistance and diabetes risk indices, finding improvements across various interventions.

Aerobic exerciseLifestyle intervention for prediabetesResistance training+2 more
RCTsAdded Sep 12, 2026

Exercise May Improve Sensory Nerve Function in Diabetics

This study investigated the effects of various exercise interventions on peripheral nerve function in diabetic patients, finding no significant alterations in nerve function.

Aerobic exerciseIsokinetic strength exerciseSedentary control+4 more
RCTsAdded Sep 12, 2026

Exercise Reduces Fat and Blood Sugar in Prediabetes

This study investigated the effects of aerobic and resistance training on abdominal fat and fasting glucose levels in adults with prediabetes, finding significant reductions in both interventions compared to a control group.

Aerobic exerciseControl Group Usual ActivityResistance training+6 more
RCTsAdded Sep 9, 2026

Family-Based Intervention May Reduce T2DM Risk Factors in Women with GDM

This study evaluated a family-based health promotion intervention aimed at reducing T2DM risk factors among women with recent GDM. It found significant reductions in 2-hour insulin levels, triglycerides, and odds of elevated fasting plasma glucose.

Family-based health promotion interventionBMIDecreased 2-hour insulin concentration in OGTT associated with elevated plasma CMPF concentration+3 more
RCTsAdded Sep 12, 2026

Finerenone reduces albumin levels in type 1 diabetes patients

The study examined the effects of finerenone on urinary albumin-to-creatinine ratio in adults with type 1 diabetes and chronic kidney disease, showing a significant reduction in UACR compared to placebo.

Finerenone (nonsteroidal mineralocorticoid receptor antagonist)Gastrointestinal disorders incidenceHbA1c+3 more
RCTsAdded Sep 9, 2026

FMT improves gastrointestinal symptoms in type 1 diabetes

This randomized pilot trial evaluated the effects of fecal microbiota transplantation (FMT) in patients with type 1 diabetes and gastroenteropathy, finding significant improvements in gastrointestinal symptoms.

Healthy lean-donor fecal microbiota transplantation capsulesGastrointestinal disorders incidenceIrritable Bowel Syndrome Impact Scale score+1 more
RCTsAdded Sep 9, 2026

Food Insecurity Linked to Healthy Eating in AI/AN Youth

This study examined the impact of a GDM risk reduction educational intervention on healthy eating behaviors among American Indian and Alaska Native adolescents, revealing mixed results.

GDM risk reduction educational interventionConsumption of vegetablesDays eating breakfast+4 more
RCTsAdded Sep 9, 2026

GABA shows no beta-cell regeneration in type 1 diabetes

This study investigated the effects of GABA on beta-cell regeneration in adults with long-standing type 1 diabetes, finding no significant improvements in key outcomes.

GABA 200 mgC-peptideCounter-regulatory hormone response to hypoglycemia+3 more
RCTsAdded Sep 9, 2026

Gamified CGM App Improves Glycemic Control in Children

A study evaluated a gamified continuous glucose monitor app and Dexcom G6 in children, finding significant improvements in glycemic outcomes.

Continuous glucose monitoringRemote multiprofessional educational programTime above range+1 more
RCTsAdded Sep 12, 2026

GLP-1 and DPP-4 Inhibitors Show No Effect on Gallbladder Volume

This study investigated the effects of GLP-1 receptor agonists and DPP-4 inhibitors on gallbladder volume and bile acid profiles in type 2 diabetes patients, finding significant changes in bile acid levels with liraglutide and sitagliptin.

LiraglutideSitagliptinChange in Serum IL-1β Levels+6 more
RCTsAdded Sep 12, 2026

Group Training Improves Daily Living for Older Adults with Diabetes

This study investigated the effects of group-based physical-cognitive training on older adults with Type 2 diabetes and balance impairment, finding significant improvements in balance and daily living activities.

Social Cognitive Theory-based group (TBG)ASTActivities of daily living+5 more
RCTsAdded Sep 10, 2026

High-Dose Oral Insulin Shows No Benefit in Type 1 Diabetes Progression

This study evaluated the effects of high-dose oral insulin in children with Stage 1 Type 1 Diabetes. It found no significant difference in progression to dysglycemia or immune response compared to placebo.

Oral insulinGlycemic control comparison to commercial AID systemsMean arterial pressure reduction
RCTsAdded Sep 9, 2026

Higher TI Dosing Needed for Effective Glucose Management

This study evaluated the dosing patterns of Technosphere insulin in adults with Type 1 diabetes, finding significant increases in total daily doses over 30 weeks.

Insulin degludecPercentage of participants increasing TI dose by >4 U at week 17Percentage of participants increasing TI dose by >4 U at week 30+4 more
RCTsAdded Sep 9, 2026

Home-based intervention may help prevent diabetes in women with GDM

This feasibility study evaluated a home-based lifestyle modification intervention for women with gestational diabetes mellitus. The results showed unclear effectiveness in key health outcomes.

Lifestyle intervention for prediabetesBody Mass Index (BMI) changeExperience with text message reminders+8 more
RCTsAdded Sep 9, 2026

IGF-1 Linked to Bone Health in Type 1 Diabetes

This study investigated the link between glycemic control and bone health in adolescents with poorly controlled Type 1 Diabetes, finding no significant changes in HbA1c levels but some variations in bone mineral density.

Control Group Usual ActivityMotivational Interviewing (tDNA-MI)Bone Mineral Density z-scores at Proximal Femur+5 more
RCTsAdded Sep 12, 2026

iGlarLixi improves glycaemic control in adults with T2D.

The study evaluated iGlarLixi's effectiveness in improving glycaemic control in Chinese adults with T2D compared to IDegAsp, showing better outcomes with lower insulin doses.

Insulin aspartInsulin glargine/lixisenatide fixed-ratio combination (iGlarLixi)Hypoglycemia events+2 more
RCTsAdded Sep 9, 2026

IMB Intervention Improves Outcomes in Gestational Diabetes

This study evaluated the effectiveness of an Information-Motivation-Behavioral Skills (IMB) model-based nursing intervention for gestational diabetes. The IMB intervention significantly improved several health outcomes compared to traditional health education.

Lifestyle intervention for prediabetesEmergency cesarean section rateFasting Plasma Glucose (FPG)+4 more
RCTsAdded Sep 9, 2026

Innovative health education improves outcomes for gestational diabetes

This study evaluated the integration of King's Theory of Goal Attainment with FMEA-PDCA in health education for gestational diabetes, finding significant improvements in fasting plasma glucose and anxiety levels.

Conventional health education groupCotransplantation of adipose tissue-derived insulin-secreting mesenchymal stem cells and hematopoietic stem cellsAnxiety+5 more
RCTsAdded Sep 12, 2026

Intervention may stabilize diabetes-related distress in newly diagnosed patients

This study evaluated the impact of a structured primary care intervention on diabetes distress in individuals with newly diagnosed type 2 diabetes, finding significant effects on interpersonal distress but not on overall distress scores.

Structured, inter-sectoral primary care interventionDiabetes Distress Scale scoreDiabetes distress scores+2 more
RCTsAdded Sep 9, 2026

Intranasal Naloxone May Preserve Hypoglycemia Responses in T1D

This study investigated the pharmacokinetics of intranasal naloxone in adults with Type 1 diabetes during exercise, revealing variable plasma concentrations without significant hypoglycemic response correlations.

Intranasal naloxoneSaline (placebo)Counter-regulatory hormone response to hypoglycemia+2 more
RCTsAdded Sep 9, 2026

isCGM plus DSME improves time in range for adults with type 2 diabetes.

This post hoc analysis of the IMMEDIATE study evaluated the impact of intermittent subcutaneous continuous glucose monitoring (isCGM) combined with diabetes self-management education (DSME) on time in range (TIR) for participants with type 2 diabetes (T2D) aged under and over 65 years.

DSMESGlucose Measurement Satisfaction Survey scoreHbA1c+1 more
RCTsAdded Sep 9, 2026

isCGM use may decrease mean glucose in newly diagnosed T1DM adults

This study evaluated the impact of intermittently scanned continuous glucose monitoring (isCGM) on glycemic control and fear of hypoglycemia in adults with newly diagnosed type 1 diabetes.

Continuous glucose monitoringFear of hypoglycemia (worry)Percentage of time spent below 70 mg/dL+2 more
RCTsAdded Sep 12, 2026

Ketoanalogues may slow eGFR decline in type 2 diabetes patients

This study investigated the effects of a low-protein diet supplemented with ketoanalogues on kidney function in patients with type 2 diabetes, finding a slower decline in eGFR compared to a standard low-protein diet.

Low-protein dietAll-cause mortalityComposite multimorbidity score+4 more
RCTsAdded Sep 12, 2026

Ketogenic Diet Reduces Proinsulin More Than Low-Fat Diet

This study compared the effects of a ketogenic diet and a low-fat diet on proinsulin levels in individuals with type 2 diabetes, finding that the ketogenic diet led to a greater reduction in proinsulin levels.

Low-carbohydrate dietLow-fat diet190-minute proinsulin to C-peptide ratio (PICP 190)+2 more
RCTsAdded Sep 12, 2026

Ketogenic diets do not improve glucose control in T2D

This study investigated the effects of low carbohydrate ketogenic diets on glucose tolerance and insulin sensitivity in obese patients with type 2 diabetes, finding no beneficial effects.

Low-carbohydrate dietStandard diet2-hour plasma glucose+6 more
RCTsAdded Sep 9, 2026

Lifestyle interventions reduce gestational diabetes risk in high-risk pregnant women

This study evaluated the impact of lifestyle interventions on pregnancy outcomes in women at high risk for gestational diabetes mellitus. It found significant reductions in the risks of gestational diabetes and pregnancy-induced hypertension.

Lifestyle intervention for prediabetesEmergency cesarean section rateGestational diabetes mellitus incidence+3 more
RCTsAdded Sep 12, 2026

Low-carb diet benefits fade after one year.

This study compared the effects of a low-carbohydrate diet and calorie restriction on HbA1c and BMI one year later, finding no significant differences.

Calorie-restricted vegetarian dietLow-carbohydrate dietBMI+1 more
RCTsAdded Sep 10, 2026

Low-Carbohydrate Supplement Lowers Blood Glucose in Prediabetes

A study assessed the impact of a low carbohydrate oral nutritional supplement on blood glucose levels in individuals with prediabetes, finding significant improvements compared to a standard supplement.

Low carbohydrate oral nutritional supplement (LC-ONS)Blood glucoseGlucose iAUC (OGTT)+4 more
RCTsAdded Sep 9, 2026

Low-GI Diet Improves Glycemic Control in High-Risk Adults

This study identified differential glycemic responders among adults at elevated risk of Type 2 diabetes through a randomized controlled trial comparing high and low-glycemic index diets.

High-Glycemic Index DietLow glycemic index treatment (LGIT)Blood glucose+3 more
RCTsAdded Sep 12, 2026

Mobile App May Improve Glucose Management in Diabetes

This pilot randomized controlled trial evaluated the efficacy of the PROTEIN mobile app for glucose management in adults with prediabetes or type 2 diabetes, finding an increase in time in range.

PROTEIN mobile appBody weightFasting Plasma Glucose (FPG)+2 more
RCTsAdded Sep 9, 2026

Mobile-based intervention may reduce metabolic syndrome risk in postpartum women

This study evaluated the efficacy of a blended mobile-based lifestyle intervention for women with glucose intolerance following gestational diabetes mellitus. The intervention showed promising results in achieving weight goals and reducing metabolic syndrome incidence.

Lifestyle intervention for prediabetesFrequency of glucose intoleranceIncidence of Metabolic Syndrome at 3 Years Postpartum+4 more
RCTsAdded Sep 12, 2026

Mobile health app may improve lifestyle change for diabetes risk

This study evaluated the feasibility of a mobile health app, Plunde, for promoting lifestyle changes in individuals at risk of Type 2 diabetes. It found significant reductions in body weight and waist circumference among app users.

Reducing Emotional Distress for Childhood Hypoglycemia in Parents (REDCHiP)App adherenceApp motivation score+4 more
RCTsAdded Sep 9, 2026

Myo-Inositol Reduces Gestational Diabetes Risk

This study investigated the effect of Myo-Inositol on preventing gestational diabetes mellitus (GDM) and found a significant reduction in GDM incidence.

Myo-inositol plus folic acidPlacebo plus folic acidGestational diabetes mellitus incidence+5 more
RCTsAdded Sep 10, 2026

Omega-3 supplementation improves glycemic control in type 2 diabetes

This study investigated the effects of omega-3 fatty acids coadministered with glimepiride on glycemic control in patients with type 2 diabetes mellitus (T2DM). It found significant reductions in fasting plasma glucose and glycated hemoglobin levels.

1 g omega-3 fatty acids dailyPlacebo with glimepirideAtherogenic Index of Plasma Increase+8 more
RCTsAdded Sep 9, 2026

One-step method increases gestational diabetes prevalence.

This study compared the one-step and two-step methods for diagnosing gestational diabetes mellitus (GDM) and found that the one-step method significantly increased GDM prevalence.

One-step method (75-gm 2-h OGTT)Two-step method (50-gm GCT followed by 100-gm OGTT)Incidence of macrosomia+3 more
RCTsAdded Sep 9, 2026

One-step OGTT may increase GDM diagnosis without improving outcomes

This study compared two strategies for screening gestational diabetes: a two-step oral glucose tolerance test (OGTT) and a one-step OGTT. The one-step approach showed a numerically higher prevalence of gestational diabetes, but the difference was not statistically significant.

One-step method (75-gm 2-h OGTT)Two-step method (50-gm GCT followed by 100-gm OGTT)Caesarean section rate+6 more
RCTsAdded Sep 9, 2026

Pilates improves nutritional status and quality of life in older adults with diabetes

This study evaluated the impact of a 12-week Pilates intervention on nutritional status and health-related quality of life in older adults with Type 2 diabetes, finding significant improvements in various health metrics.

Pilates-based exercise programChange in Bodily Pain Domain of Health-Related Quality of LifeChange in role physical domain of health-related quality of life+6 more
RCTsAdded Sep 12, 2026

POLYCHEM shows no superiority over standard care for diabetes remission

This study compared a four-drug regimen (POLYCHEM) to standard diabetes care (SDC) in newly diagnosed type 2 diabetes patients, finding no significant difference in diabetes remission but a notable improvement in hyperglycemia regression with POLYCHEM.

POLYCHEMStandard face-to-face careDiabetes remission+1 more
RCTsAdded Sep 9, 2026

Probiotics Improve Metabolic Outcomes in Post-GDM Women

This study investigated the effects of probiotics on metabolic outcomes in women with a history of gestational diabetes, finding significant improvements in fasting plasma glucose and other metabolic markers.

ProbioticsC-reactive proteinFasting Plasma Glucose (FPG)+4 more
RCTsAdded Sep 12, 2026

Probiotics may improve postprandial blood glucose in type 2 diabetes

This study investigated the effects of multi-strain probiotic supplementation on glucose and lipid metabolism in patients with type 2 diabetes. It found significant reductions in fasting and postprandial blood glucose levels.

Multi-species synbiotic (12 probiotic strains + FOS prebiotic)C-reactive proteinFasting Plasma Glucose (FPG)+5 more
RCTsAdded Sep 9, 2026

Real-Time CGM Improves Glycemic Control in Type 2 Diabetes

This study evaluated the effectiveness of real-time continuous glucose monitoring (rtCGM) compared to self-monitoring of blood glucose (SMBG) in adults with insulin-requiring type 2 diabetes, finding significant improvements in glucose control with rtCGM.

Continuous glucose monitoringExtended hyperglycaemic event rate/week >13.9 mmol/LGlucose management indicator (GMI)+8 more
RCTsAdded Sep 9, 2026

Real-time glucose monitoring improves engagement in type 2 diabetes management

This study explored the experiences of individuals with Type 2 Diabetes using real-time continuous glucose monitoring (rtCGM) while on insulin. Participants reported significant improvements in glycaemia and overall well-being.

Continuous glucose monitoringBarriers to continual usage of rtCGM technologyImproved adherence to medication+4 more
RCTsAdded Sep 12, 2026

Replacing Sucrose with Sucralose Shows Little Effect on Glycemia

This study evaluated the impact of substituting sucrose with sucralose in coffee/tea on glycemic control in individuals with type 2 diabetes. It found significant reductions in body weight, BMI, and waist circumference.

Sucralose substitution in coffee/teaBMIBody weight+7 more
RCTsAdded Sep 12, 2026

Resistance exercise may improve glycemic stability in type 1 diabetes

This study compared glycemic stability and hypoglycemic episodes during aerobic and resistance exercises in patients with Type 1 Diabetes, finding no significant differences in glucose levels or hypoglycemic episodes between the exercise types.

Aerobic exerciseTaichi plus resistance band training24-hour glucose+4 more
RCTsAdded Sep 12, 2026

Resistance training may improve health status in type 2 diabetes

This study compared the effects of Progressive Resistance Training (PRT) and Aerobic Training (AT) on health status in adults with Type 2 Diabetes, revealing improvements in various health outcomes.

Exercise therapyResistance trainingGeneral Health Management Improvement+3 more
RCTsAdded Sep 9, 2026

RT-CGM Enhances Glycemic Control in Prediabetes

This study evaluated the impact of real-time continuous glucose monitoring (RT-CGM) on glycemic control in prediabetes. The RT-CGM group showed significant improvements in HbA1c compared to controls.

Continuous glucose monitoringBMIFasting Plasma Glucose (FPG)+3 more
RCTsAdded Sep 12, 2026

Selenium-Enriched Eggs Improve Glycemic Control in Diabetes

This study compared the effects of selenium-enriched eggs and zeaxanthin-enriched eggs on glycemic and lipid metabolism in patients with type 2 diabetes, finding significant reductions in fasting plasma glucose and triglycerides.

Selenium-enriched eggsZeaxanthin-enriched eggsFasting Plasma Glucose (FPG)+4 more
RCTsAdded Sep 9, 2026

Self-management model improves outcomes for pregnant women with diabetes

This study evaluated the effects of a self-management-clustered pregnancy care model on pregnant women with gestational diabetes mellitus, finding significant improvements in self-management abilities and health outcomes.

Self-management-cluster-based pregnancy care model (SMB-CPCM)Anxiety scale scoresDepression self-assessment scale scores+7 more
RCTsAdded Sep 9, 2026

Self-transcendence nursing improves outcomes in GDM patients

This study evaluated the self-transcendence nursing model's effectiveness in managing gestational diabetes mellitus (GDM) patients compared to routine nursing care.

Self-transcendence nursing modelDiabetes Distress Scale scoreDiabetes self-management behaviors+6 more
RCTsAdded Sep 12, 2026

Semaglutide enhances insulin response in type 2 diabetes

The study evaluated the effects of semaglutide on beta cell function and glycaemic control in type 2 diabetes, finding significant improvements in insulin secretion and glucose levels.

Subcutaneous SemaglutideFasting Plasma Glucose (FPG)Glucagon response (AUC 0-24h)+4 more
RCTsAdded Sep 12, 2026

SiPore21 improves glycaemic control in prediabetes

The study evaluated SiPore21's effects on glycaemic control and metabolic health in adults with prediabetes or early type 2 diabetes, finding significant improvements in several health markers.

SiPore21Body fat massBody weight+5 more
RCTsAdded Sep 9, 2026

Social support improves gestational diabetes management

This study explored the role of social support in managing gestational diabetes mellitus (GDM) through postpartum patient navigation. Findings indicated various forms of support and barriers faced by individuals.

Postpartum patient navigation for individuals with GDMBarriers of social supportCommunity support for diabetes management+2 more
RCTsAdded Sep 9, 2026

Sotagliflozin improves kidney function in type 1 diabetes

The study investigated the effects of sotagliflozin on copeptin levels and kidney injury in participants with type 1 diabetes, finding significant increases in copeptin and reductions in kidney injury markers.

SotagliflozinCopeptinFractional Excretion of Glucose (FE Glucose)+6 more
RCTsAdded Sep 12, 2026

SugarVita may improve HbA1c in adults with type 2 diabetes

This pilot randomized controlled trial evaluated the effects of SugarVita, a serious game for diabetes self-management, compared to standard care. The intervention group showed a significant reduction in HbA1c levels.

SugarVita plus standard careDiabetes knowledgeHbA1c+2 more
RCTsAdded Sep 12, 2026

Switching to weekly insulin icodec improves glycemic control

The ONWARDS 10 trial evaluated the switch from daily basal insulin to once-weekly insulin icodec, finding improvements in HbA1c and time in range compared to glargine U100.

Glargine U100Once-weekly insulin icodecEfficacy of Cognitive Behavioral Therapy (CBT) in Diabetes Management+2 more
RCTsAdded Sep 9, 2026

Tailored diabetes education improves self-efficacy in Chinese Americans

A pilot randomized controlled trial found that a culturally tailored diabetes education program improved self-efficacy and dietary adherence among Chinese Americans with Type 2 diabetes.

Stepped care diabetes prevention program with financial incentivesAdherence to a healthy dietDiabetes distress scores+1 more
RCTsAdded Sep 9, 2026

Telephone support for lifestyle changes shows no reduction in diabetes incidence

This study evaluated a postpartum telephone-based lifestyle intervention for women at high risk of diabetes after gestational diabetes mellitus. The findings indicated no significant reduction in diabetes incidence or weight gain.

Normal carePostpartum telephone support for lifestyle changesDiscrepancy between clinically measured weight and self-reported weight associated with BMI+1 more
RCTsAdded Sep 12, 2026

Toe Resistance Training Improves Strength in Diabetes Patients

This study investigated the effects of resistance training on toe pinch force in chronic hemodialysis patients with type 2 diabetes, finding significant improvements in the intervention group.

Aerobic exerciseResistance trainingRate of Continuation of Exercise Therapy+1 more
RCTsAdded Sep 12, 2026

Triple therapy may improve glycaemic control in Type 1 Diabetes

This study evaluated the efficacy and safety of adding a GLP-1 receptor agonist and SGLT2 inhibitor to insulin therapy in Type 1 Diabetes, finding significant improvements in HbA1c and quality of life.

Dapagliflozin and Semaglutide and InsulinInsulin therapyDiabetic ketoacidosis+5 more
RCTsAdded Sep 9, 2026

Ustekinumab improves beta-cell function in type 1 diabetes

This study evaluated the effects of ustekinumab in adolescents with recent-onset type 1 diabetes, finding significant improvements in C-peptide levels and reductions in specific T cell populations.

UstekinumabC-peptide incremental area under the curve (iAUC)Cytokine production from T-helper 2 cells+1 more
RCTsAdded Sep 9, 2026

Video Intervention Improves Medication Adherence in Older Adults with Diabetes

The study evaluated the impact of the 'Diabetes Little Helper' video intervention on medication adherence among older adults with Type 2 diabetes, finding significant improvements in various adherence-related scores.

Diabetes Little Helper video interventionAttitude score measured before and after interventionDiabetes social support+4 more
RCTsAdded Sep 12, 2026

Vitamin D3 and Flaxseed Oil Reduce Inflammation in Diabetes

This study investigated the effects of cosupplementation with high-dose vitamin D3 and flaxseed oil on inflammation in elderly patients with type 2 diabetes mellitus (T2DM), finding significant reductions in several inflammatory markers.

Vitamin D supplementationBMIBody weight+8 more

Entities

New Interventions & Outcomes

New intervention and outcome entities created during this weekly snapshot.

No new intervention or outcome entities were added this week.

EvidenceScore™

EvidenceScore™ Changes

Evidence Upgrade

Aerobic Exercise -> Blood Pressure

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Body Composition

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Body Weight

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> CGM Time in Range

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Fasting Glucose

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Insulin Resistance

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Postprandial and OGTT Glucose

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Quality of Life Outcomes

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Sleep Outcomes

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Alpha-glucosidase inhibitors -> Insulin Resistance

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Alpha-glucosidase inhibitors -> Postprandial and OGTT Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> Adipokine and Angiogenic Markers

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> Body Mass Index

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> Fasting Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> Insulin Resistance

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Adipokine and Angiogenic Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Body Mass Index

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Inflammatory Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Insulin Resistance

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Oxidative Stress Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Digital Lifestyle Interventions -> Adipokine and Angiogenic Markers

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Digital Lifestyle Interventions -> Fasting Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Digital Lifestyle Interventions -> Insulin Resistance

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Digital Lifestyle Interventions -> Mental Health

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

DPP-4 Inhibitors -> Body Composition

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

DPP-4 Inhibitors -> Insulin Resistance

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

DPP-4 Inhibitors -> Kidney Function

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Blood Pressure

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Body Weight

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Diabetes Incidence and Prevention

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Hypoglycemia

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Mental Health

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

GLP-1 Receptor Agonists -> Glucose Variability

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Adipokine and Angiogenic Markers

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Body Mass Index

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Body Weight

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Fasting Glucose

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Glucose Variability

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Hypoglycemia

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Postprandial and OGTT Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Therapies -> Blood Pressure

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Therapies -> Kidney Function

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Therapies -> Treatment Experience

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Adipokine and Angiogenic Markers

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Blood Pressure

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Body Mass Index

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Body Composition

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Body Weight

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Fasting Glucose

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Quality of Life Outcomes

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Blood Pressure

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Body Mass Index

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Body Weight

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> CGM Time in Range

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Fasting Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Glucose Variability

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> HbA1c

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Insulin Resistance

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Mental Health

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Physical Activity Levels

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Postprandial and OGTT Glucose

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Metformin Therapies -> Adipokine and Angiogenic Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Metformin Therapies -> Blood Pressure

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Metformin Therapies -> Body Composition

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

mHealth Diabetes Support Interventions -> Diabetes Management Self-Efficacy

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

mHealth Diabetes Support Interventions -> Mental Health

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

mHealth Diabetes Support Interventions -> Postprandial and OGTT Glucose

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

mHealth Diabetes Support Interventions -> Quality of Life Outcomes

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Mind-Body and Balance Exercise -> CGM Time in Range

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Mind-Body and Balance Exercise -> Fasting Glucose

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Mind-Body and Balance Exercise -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Mind-Body and Balance Exercise -> Insulin Resistance

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Mind-Body and Balance Exercise -> Postprandial and OGTT Glucose

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Probiotics and Synbiotics -> Oxidative Stress Markers

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Probiotics and Synbiotics -> Postprandial and OGTT Glucose

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Blood Pressure

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Body Mass Index

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Body Composition

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> CGM Time in Range

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Glucose Variability

Emerging -> Emerging

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Insulin Resistance

Moderate -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Quality of Life Outcomes

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Sulfonylureas -> Adipokine and Angiogenic Markers

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Sulfonylureas -> Fasting Glucose

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Telehealth Interventions -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Thiazolidinediones -> Adipokine and Angiogenic Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Thiazolidinediones -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Thiazolidinediones -> Insulin Resistance

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Downgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Kidney Function

Moderate -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

GLP-1 Receptor Agonists -> Retinopathy

Emerging -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Metformin Therapies -> Hypoglycemia

Moderate -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Probiotics and Synbiotics -> Body Composition

Moderate -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Probiotics and Synbiotics -> Insulin Resistance

Strong -> Strong

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Probiotics and Synbiotics -> Kidney Function

Moderate -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

SGLT2 Inhibitors -> Urinary Tract Infections

Strong -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Updates

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