RESEARCH SUMMARY

Home resistance training and leisure activity both improve blood sugar and boost helpful GLP-1 hormone in children with type 1 diabetes

Low confidence
Some Concerns bias
Last updated May 7, 2026

Key takeaway:

An 8-week study of 20 children with type 1 diabetes found that both home-based resistance training and leisure-time physical activities improved blood sugar control and increased GLP-1 hormone levels, with resistance training showing greater cardiovascular benefits.

Study at a glance

Study type

RCTs

duration

Short-Term (≤3 mo)

Intervention

Resistance training, Aerobic exercise

Outcomes

Fasting Plasma Glucose, GLP-1, MicroRNA-192, VO2 max, HbA1c, Fasting insulin levels, Fasting Plasma Glucose, GLP-1, MicroRNA-192, VO2 max, HbA1c

Funding

Non-industry sponsored

What was studied

8-week exercise interventions in children with type 1 diabetes

What they found

  • ↓ Fasting blood glucose (30-35 mg/dL reduction in both groups)
  • ↑ GLP-1 hormone levels (2.5-3.7 pg/mL increase)
  • ↓ MicroRNA-192 levels (58-60% decrease in both groups)
  • ↑ Cardiovascular fitness (greater in resistance training group)

mainEffects

↓ Fasting blood glucose (30-35 mg/dL reduction in both groups)

↑ GLP-1 hormone levels (2.5-3.7 pg/mL increase)

↓ MicroRNA-192 levels (58-60% decrease in both groups)

↑ Cardiovascular fitness (greater in resistance training group)

Evidence Suggest

  • Both structured home resistance training and self-chosen leisure activities effectively reduce fasting blood glucose in children with type 1 diabetes
  • Exercise increases GLP-1 secretion and decreases miRNA-192 expression, potentially supporting pancreatic β-cell health
  • Home-based resistance training produces superior cardiovascular fitness gains compared to leisure-time activities

Who this applies to

This research applies to children with type 1 diabetes (average age 12-13 years) who have been diagnosed for at least 2 years and are not currently engaged in regular exercise. The findings may be particularly relevant for families looking for practical, home-based or recreational physical activity options.

Keep in Mind

The study was quite small with only 20 children total, which limits how confidently we can apply these findings. The 8-week timeframe was relatively short, and longer studies are needed to see if these benefits persist and lead to meaningful improvements in long-term diabetes control (HbA1c). The leisure activity group had less structured exercise, so intensity and type varied between participants. Both groups showed improvements, but we don't know how they compare to children who don't exercise at all.

Between the Lines

  • Very small sample size (10 participants per group) limits statistical power and generalizability
  • Short 8-week duration may be insufficient to detect HbA1c changes
  • No true control group (no exercise comparison)
  • Exercise intensity in leisure group was not controlled or monitored

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Sources

guidelines

ADA Standards of Care in Diabetes—2025: Physical Activity and Exercise

The American Diabetes Association's clinical practice guidelines recommend regular physical activity for all people with type 1 diabetes, including children and adolescents, emphasizing both aerobic and resistance exercise for optimal metabolic and cardiovascular benefits.
guidelines

ISPAD Clinical Practice Consensus Guidelines: Exercise in Children and Adolescents with Diabetes

International Society for Pediatric and Adolescent Diabetes guidelines provide evidence-based recommendations for exercise management in youth with type 1 diabetes, addressing safety considerations, glucose monitoring, and strategies to prevent exercise-related hypoglycemia.
guidelines

Episode 59: Early Detection of Type 1 Diabetes | American Association of Clinical Endocrinology

This podcast discusses the growing prevalence of Type 1 Diabetes (T1D), the importance of autoantibody screening, the different stages of T1D, screening guidelines, patient counseling, and how early intervention can help delay progression and reduce complications.
guidelines

Standards of Care in Diabetes—2024

Annual ADA clinical practice guideline issue covering broad diabetes management.
guidelines

Anaerobic Exercise & Diabetes | ADA

Aerobic exercise improves heart health, increases your metabolism, aids weight loss, lowers your blood pressure, increases your HDL (“good”) cholesterol and boosts your mood.
guidelines

Diabetes Type Confusion | ADA

Type 1 diabetes is often mistakenly thought of as a childhood disease. However, it is estimated that half of all new type 1 diagnoses develop after the age of 20.
guidelines

Driver's License Information | ADA

Individuals with type 1 diabetes and those with type 2 diabetes at risk for low blood glucose should take steps to avoid lows when driving.
healthAuthorities

CDC: Physical Activity for People with Diabetes

Provides accessible guidance on the benefits and practical considerations of physical activity for diabetes management, including safety tips and activity recommendations appropriate for various age groups.
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Effects of resistance training on the glycemic control of people with type 1 diabetes: a systematic review and meta-analysis.

2022
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Management of Glycemia during Acute Aerobic and Resistance Training in Patients with Diabetes Type 1: A Croatian Pilot Study.

2023
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Glucagon-like peptide-1 agonists' effects on glycemic control, weight loss, and beta cells function in type 1 diabetes.

2026
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Effects of 12-week combined interval running and resistance training on cardiac structure and performance in patients with type 1 diabetes.

2025
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The Efficacy of Short-Term Toe Resistance Training in Chronic Hemodialysis Patients with Type 2 Diabetes.

2023

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