Understanding Artificial Pancreas Systems: Results from a 24-Month Trial

Related and Discussions

Subscribe now for the latest breakthroughs, expert insights, and cutting-edge updates in diabetes care—delivered straight to your inbox.

Stay informed. Stay ahead.

The Mediterranean diet reduced gestational diabetes rates by over 40%. In the main study, 15% of women in the intervention group developed gestational diabetes versus 26% in the control group. The real-world group showed similar benefit with 13% developing gestational diabetes. These results were consistent and meaningful across both settings.

HbA1c levels were lower in both intervention groups throughout pregnancy. At mid-pregnancy, women in intervention groups averaged 5.0% compared to 5.1% in controls. Later in pregnancy, the difference was larger: 5.3% in intervention groups versus 5.5% in controls. Fewer women in intervention groups had HbA1c above 5.5% late in pregnancy.

Results varied for insulin resistance. Women who received free olive oil and nuts showed lower insulin resistance throughout pregnancy. However, the real-world group without free foods showed no clear benefit. This suggests the effect depends on how closely women can follow the diet.

Urinary tract infections were much less common in both intervention groups. About 7% of women in intervention groups had infections, compared to 19% in the control group. This benefit was consistent whether or not women received free foods.

Emergency cesarean sections were much less common in intervention groups. Only about 2% needed emergency cesareans, compared to 8% in the control group. This benefit was seen in both the main study and real-world groups.

Birth injuries were much less common in intervention groups. Only 2-3% experienced perineal tears, compared to 11% in the control group. This benefit was strong and consistent across both study groups.

with extra virgin olive oil (≥40 mL/day) and pistachios (25-30g, ≥3 days/week)

These results match earlier research on Mediterranean diet during pregnancy. The benefits appear stronger than some other dietary approaches that focused mainly on calorie restriction.

The study is important because it shows the diet works in real-world clinical settings, not just in controlled research. Hispanic women have higher gestational diabetes risk than many other groups, so finding an effective prevention approach matters.

This was a well-designed study with over 500 women. The results were clear and consistent.

However, participants knew which diet they were following. This could affect how they reported their eating habits. The study focused on Hispanic women in Spain, so results may not apply to other populations.

A Mediterranean diet with olive oil and pistachios started early in pregnancy may reduce gestational diabetes risk by about 40% in Hispanic women

Women following this diet had better blood sugar control and needed insulin less often if gestational diabetes developed

The benefits were consistent in both research and real-world settings, though adherence was better when foods were provided free

The results suggest a Mediterranean diet may help prevent gestational diabetes in Hispanic women

Evidence is strongest for reducing gestational diabetes risk, with consistent benefits seen across different settings

Some benefits like reduced birth complications were less consistent when women had to buy their own foods

The diet also appears to improve blood sugar control and reduce pregnancy complications beyond just preventing gestational diabetes

This approach can work in routine care, though providing food supplies may improve how well women follow the diet

Women in the intervention group started a Mediterranean diet at 12-14 weeks of pregnancy. They were told to use at least 40 mL of olive oil daily and eat about one handful of pistachios at least 3 days per week. Free olive oil and pistachios were provided to help them follow this plan.

A dietician met with participants to reinforce the dietary recommendations and answer questions. The real-world group got the same advice but without free foods.

The control group received standard prenatal nutrition advice to limit dietary fat, with olive oil kept under 40 mL daily and nuts eaten less than 3 days per week.

Mediterranean diet, extra virgin olive oil supplementation, pistachio nut supplementation, dietary counseling, nutritional intervention

Melero V, García de la Torre N, Assaf-Balut C, et al. Effect of a Mediterranean Diet-Based Nutritional Intervention on the Risk of Developing Gestational Diabetes Mellitus and Other Maternal-Fetal Adverse Events in Hispanic Women Residents in Spain. Nutrients. 2020;12(11):3505. doi:10.3390/nu12113505

The Mediterranean diet cut gestational diabetes rates by more than 40%. Only 15% of women in the intervention group developed gestational diabetes, compared to 26% in the control group. The real-world group showed similar results with a 13% rate.

Women following the Mediterranean diet had better blood sugar control throughout pregnancy. When gestational diabetes did develop, fewer women needed insulin therapy compared to the control group. The diet also reduced urinary tract infections, emergency cesarean sections, and birth injuries.

Participants were not blinded to their diet group

Results apply specifically to Hispanic women in Spain

Diet adherence was lower without free food provision

Mediterranean diet may reduce gestational diabetes risk by 40% in Hispanic women.

Participants knew which group they were in, which may have influenced their behavior and reporting. Dietary intake was measured through questionnaires, which rely on memory and can be affected by what people think they should report.

The study included only Hispanic women living in Spain. Results may differ for Hispanic women in other countries or for other ethnic groups. When women had to buy their own olive oil and nuts instead of getting them free, they followed the diet less closely.

Gestational diabetes → ↓ (strong reduction)

Blood sugar control → ↓ (moderate improvement)

Pregnancy complications → ↓ (moderate reduction)

ADA Standards of Care - Gestational Diabetes Management 2024

Mayo Clinic: Mediterranean Diet During Pregnancy

Joslin Diabetes Center: Nutrition and Gestational Diabetes

This study took place in Madrid, Spain from 2015-2017. Pregnant Hispanic women were enrolled early in pregnancy at 8-12 weeks. All participants had normal blood sugar at the start.

Women were randomly assigned to different groups. The control group received standard advice to limit fat. The intervention group received Mediterranean diet guidance with at least 40 mL of olive oil daily and pistachios 3+ days per week, with free supplies provided. A third group received the same dietary advice but had to buy their own foods.

Participants attended four visits during pregnancy. At 24-28 weeks, they were tested for gestational diabetes. Diet adherence was checked at each visit using questionnaires about their eating habits.

Mediterranean diet reduces gestational diabetes risk by 40% in Hispanic women

This study tested whether a Mediterranean diet could prevent gestational diabetes in Hispanic pregnant women.

Researchers enrolled 600 Hispanic women early in pregnancy. Some received Mediterranean diet guidance with free olive oil and pistachios. Others got standard dietary advice to limit fat intake.

Women following the Mediterranean diet had much lower rates of gestational diabetes. Only 15% developed it, compared to 26% in the standard care group. They also had better blood sugar control and fewer pregnancy complications.

The benefits were consistent and meaningful. The study shows this dietary approach works well for preventing gestational diabetes in Hispanic women.

Participants knew which diet they were following, which could affect results

The study focused on Hispanic women in Spain, so results may not apply to all populations

Cost and access to olive oil and nuts may make it harder to follow this diet without financial support

A trial of 600 Hispanic pregnant women testing Mediterranean diet for gestational diabetes prevention

Pregnant Hispanic women, particularly those at higher risk for gestational diabetes

Pregnant Hispanic women at risk for gestational diabetes mellitus

This study tested whether a Mediterranean diet could prevent gestational diabetes in Hispanic pregnant women.
Researchers enrolled 600 Hispanic women early in pregnancy. Some received Mediterranean diet guidance with free olive oil and pistachios. Others got standard dietary advice to limit fat intake.
Women following the Mediterranean diet had much lower rates of gestational diabetes. Only 15% developed it, compared to 26% in the standard care group. They also had better blood sugar control and fewer pregnancy complications.
The benefits were consistent and meaningful. The study shows this dietary approach works well for preventing gestational diabetes in Hispanic women.

Mediterranean diet reduces gestational diabetes risk by 40% in Hispanic women

Study at a glance

What was studied

What they found

mainEffects

Evidence Suggest

Who this applies to

Keep in Mind

Between the Lines

Unlock Full Analysis

No ads. No tracking

Secure & private

Always up to date